Urinary 8-OHdG is a highly reliable biomarker that can detect genetic DNA damage caused by active oxygen sensitively, and is a test for rust.
When the gene DNA is damaged by the action of active oxygen and part of the gene rusts, 8-hydroxy-deoxyguanosine (8-OHdG) is produced by oxidation. The rusty damaged gene DNA is repaired immediately, but 8-OHdG that is no longer needed for repair is excreted in the blood, which is excreted from the blood into the urine.
Therefore, measurement of urinary 8-OHdG measures the amount of genetic DNA damaged by oxidation. It is to know the degree of rusting of the body due to oxidative stress, and it is not necessarily related to the degree of rusting of the gene, but also related to the progression of most diseases and aging such as arteriosclerosis and myocardial infarction.
If this value is lower, not so much under the influence of oxidative stress, I say okay in the lifestyle of the remains of now, the higher the value, cancer, lifestyle-related diseases, for anti-aging, lifestyle It means that some improvement is necessary.
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